Article
Duplication of two distinct regions on chromosome 5q in non-papillary renal-cell carcinomas.
International journal of cancer - 4 May 1998
Bugert P, Von Knobloch R, Kovacs G
Abstract excerpt
RFLP studies have indicated a duplication of DNA sequences at the chromosome 5q22 region and showed a breakpoint cluster between the apc and mcc genes in nonpapillary renal-cell carcinoma (RCC). We have now made a high-density fluorescent microsatellite assay to investigate the allelic status and determine the smallest duplication at this region in 62 sporadic non-papillary RCCs. Duplication at each informative...
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