Article
CD38 is functionally dependent on the TCR/CD3 complex in human T cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 May 1998
Morra M, Zubiaur M, Terhorst C, Sancho J, Malavasi F
Abstract excerpt
One of the functions of surface CD38 is the induction of phosphorylation of discrete cytoplasmic substrates and mobilization of cytoplasmic calcium (Ca2+). The present work addresses the issue of whether the signaling mediated via CD38 operates through an independent pathway or, alternatively, is linked to the TCR/CD3 signaling machinery. We studied the signals elicited through CD38 by the specific agonistic IB4...
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