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Pseudorabies Virus UL37 Gene Product Is Involved in Secondary Envelopment

1 Oct 2001

Abstract excerpt

Herpesvirus envelopment is a two-step process which includes acquisition of a primary envelope resulting from budding of intranuclear capsids through the inner nuclear membrane. Fusion with the outer leaflet of the nuclear membrane releases nucleocapsids into the cytoplasm, which then gain their final envelope by budding into trans-Golgi vesicles. It has been shown that the UL34 gene product is required for...

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Identifiers

PMID: 11533156
DOI: 10.1128/jvi.75.19.8927-8936.2001

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Pseudorabies Virus UL37 Gene Product Is Involved in Secondary EnvelopmentPMID 11533156Read ↗

Essential Function of the Pseudorabies Virus UL36 Gene Product Is Independent of Its Interaction with the UL37 ProteinSemantic proximity Read ↗

Primary envelopment of pseudorabies virus at the nuclear membrane requires the UL34 gene product.Semantic proximity Read ↗

Inner tegument protein pUL37 of herpes simplex virus type 1 is involved in directing capsids to the trans-Golgi network for envelopment.Semantic proximity Read ↗

The Pseudorabies Virus UL11 Protein Is a Virion Component Involved in Secondary Envelopment in the CytoplasmSemantic proximity Read ↗

Identification of functional domains within the essential large tegument protein pUL36 of pseudorabies virus.Semantic proximity Read ↗

The Interacting UL31 and UL34 Gene Products of Pseudorabies Virus Are Involved in Egress from the Host-Cell Nucleus and Represent Components of Primary Enveloped but Not Mature VirionsSemantic proximity Read ↗

Vesicle formation from the nuclear membrane is induced by coexpression of two conserved herpesvirus proteins.Semantic proximity Read ↗

A Physical Link between the Pseudorabies Virus Capsid and the Nuclear Egress ComplexSemantic proximity Read ↗

Phenotypic similarities and differences between UL37-deleted pseudorabies virus and herpes simplex virus type 1.Semantic proximity Read ↗

Simultaneous Deletion of Pseudorabies Virus Tegument Protein UL11 and Glycoprotein M Severely Impairs Secondary EnvelopmentSemantic proximity Read ↗

Lysine 242 within Helix 10 of the Pseudorabies Virus Nuclear Egress Complex pUL31 Component Is Critical for Primary Envelopment of NucleocapsidsSemantic proximity Read ↗

Functional characterization of nuclear trafficking signals in pseudorabies virus pUL31.Semantic proximity Read ↗

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