Article
A promoter region mutation affecting replication of the Tetrahymena ribosomal DNA minichromosome.
Molecular and cellular biology - 1 May 1998
Gallagher R C, Blackburn E H
Abstract excerpt
In the ciliated protozoan Tetrahymena thermophila the ribosomal DNA (rDNA) minichromosome replicates partially under cell cycle control and is also subject to a copy number control mechanism. The relationship between rDNA replication and rRNA gene transcription was investigated by the analysis of...
Topics
- Animals
- Cell Cycle
- Chromosomes
- DNA Footprinting
- DNA Replication
- DNA, Protozoan
- DNA, Ribosomal
- DNA-Binding Proteins
- Gene Dosage
- Mutation
- Phenotype
- Promoter Regions, Genetic
- Protein Binding
- Tetrahymena thermophila
- Transcription, Genetic