Article
A promoter region mutation affecting replication of the Tetrahymena ribosomal DNA minichromosome.
Molecular and cellular biology - 1 May 1998
Gallagher R C, Blackburn E H
Abstract excerpt
In the ciliated protozoan Tetrahymena thermophila the ribosomal DNA (rDNA) minichromosome replicates partially under cell cycle control and is also subject to a copy number control mechanism. The relationship between rDNA replication and rRNA gene transcription was investigated by the analysis of replication, transcription, and DNA-protein interactions in a mutant rDNA, the rmm3 rDNA. The rmm3 (for rDNA...
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