Article
Tetrahymena thermophila mutants defective in the developmentally programmed maturation and maintenance of the rDNA minichromosome.
Genetics - 1 Jun 1994
Kapler G M, Orias E, Blackburn E H
Abstract excerpt
The abundant rDNA minichromosome of Tetrahymena thermophila is generated by a series of developmentally controlled processing steps, termed rDNA maturation, during the formation of the new macronucleus in conjugating cells. rDNA maturation involves excision of a region encoding the single copy rRNA gene (rDNA) from its germline location, rearrangement of the rDNA into a palindromic minichromosome, de novo...
Topics
- Animals
- Base Sequence
- Blotting, Southern
- Cell Nucleus
- Crosses, Genetic
- DNA
- DNA Primers
- DNA, Ribosomal
- Genetic Linkage
- Genotype
- Molecular Sequence Data
- Mutagenesis