Article
Natural organic compounds that affect to microtubule functions.
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan - 1 Apr 1998
Iwasaki S
Abstract excerpt
Microtubules (MT), composed of a protein tubulin (TN) alpha,beta-heterodimer with concomitant other proteins, microtubule associated proteins (MAPs and tau), are known to be the main component of spindles in a mitotic apparatus of eucaryotic cells, and are also involved in many other basic and essential cell functions. There are a number of natural and synthetic compounds that interfere with MT function to cause...
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