Article
Angiotensin-converting-enzyme insertion/deletion genotype and long-term renal allograft survival.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Mar 1998
Beige J, Offermann G, Distler A, Sharma A M
Abstract excerpt
BACKGROUND: Increased activity of the renin-angiotensin system has been implicated in decreased long-term survival of renal allografts. Recent studies suggest that a deletion variant of the angiotensin-converting enzyme, associated with increased humoral and tissue activity of this enzyme, may be a risk factor for the development of diabetic nephropathy and the progression of IgA nephropathy. The present study...
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