Article
Methylenetetrahydrofolate-reductase gene C677T variant and kidney-transplant survival.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Sept 1998
Liangos O, Kreutz R, Beige J, Offermann G, Distler A, Sharma A M
Abstract excerpt
UNLABELLED: BACKGROUND. Hyperhomocysteinaemia, a risk factor for atherosclerosis, is common in haemodialysis and renal-transplant patients. As atherosclerotic lesions in hyperhomocysteinaemia resemble those of chronic allograft injury, we examined the hypothesis that the C677T variant of the meth...
Topics
- Adult
- Alleles
- Cohort Studies
- Female
- Gene Frequency
- Genetic Variation
- Genotype
- Humans
- Kidney Transplantation
- Male
- Methylenetetrahydrofolate Reductase (NADPH2)
- Middle Aged
- Mutation
- Oxidoreductases Acting on CH-NH Group Donors
- Prospective Studies
- Survival Analysis
- Time Factors