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Article

Methylenetetrahydrofolate-reductase gene C677T variant and kidney-transplant survival.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Sept 1998

Liangos O, Kreutz R, Beige J, Offermann G, Distler A, Sharma A M

Abstract excerpt

UNLABELLED: BACKGROUND. Hyperhomocysteinaemia, a risk factor for atherosclerosis, is common in haemodialysis and renal-transplant patients. As atherosclerotic lesions in hyperhomocysteinaemia resemble those of chronic allograft injury, we examined the hypothesis that the C677T variant of the methylenetetrahydrofolate reductase (MTHFR) gene, which is linked to elevated plasma homocysteine levels in patients with...

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Source

Identifiers

PMID: 9761522
DOI: 10.1093/ndt/13.9.2351

Genes

MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Methylenetetrahydrofolate-reductase gene C677T variant and kidney-transplant survival.PMID 9761522Read ↗

Effect of MTHFR genotypes and hyperhomocysteinemia on patient and graft survival in kidney transplant recipients.Semantic proximity Read ↗

Effects of single-nucleotide polymorphisms in MTHFR and MTRR on mortality and allograft loss in kidney transplant recipients.Semantic proximity Read ↗

No association of factor V Leiden, prothrombin G20210A, and MTHFR C677T gene polymorphisms with kidney allograft survival: a multicenter study.Semantic proximity Read ↗

Effect of MTHFR C677T genotype on survival in type 2 diabetes patients with end-stage diabetic nephropathy.Semantic proximity Read ↗

Hyperhomocysteinemia and MTHFR C677T and A1298C polymorphisms are associated with chronic allograft nephropathy in renal transplant recipients.Semantic proximity Read ↗

Polymorphism of the methylenetetrahydrofolate reductase C677T gene with chronic allograft nephropathy in renal transplant recipients.Semantic proximity Read ↗

Effect of the MTHFR C677T and A1298C polymorphisms on survival in patients with advanced CKD and ESRD: a prospective study.Semantic proximity Read ↗

Angiotensin-converting-enzyme insertion/deletion genotype and long-term renal allograft survival.Semantic proximity Read ↗

Cardiac allograft vascular disease after orthotopic heart transplantation: methylenetetrahydrofolate reductase gene polymorphism C677T does not account for rapidly progressive forms.Semantic proximity Read ↗

Risk factors for long-term renal survival after renal transplantation: a role for angiotensin-converting enzyme (insertion/deletion) polymorphism?Semantic proximity Read ↗

Angiotensin-converting enzyme genotype and renal allograft survival.Semantic proximity Read ↗

Interplay between methylenetetrahydrofolate reductase gene polymorphism 677C-->T and serum folate levels in determining hyperhomocysteinemia in heart transplant recipients.Semantic proximity Read ↗

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