Article
Angiotensin-converting enzyme genotype and renal allograft survival.
Journal of the American Society of Nephrology : JASN - 1 Aug 1997
Beige J, Scherer S, Weber A, Engeli S, Offermann G, Opelz G, Distler A, Sharma A M
Abstract excerpt
Increased activity of the renin-angiotensin system has been implicated in decreased, long-term survival of renal allografts. Recent studies suggest that a deletion variant of the angiotensin-converting enzyme, associated with increased humoral and tissue activity of this enzyme, is a risk factor for the development of diabetic nephropathy and the progression of IgA nephropathy. To determine whether the deletion...
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