Article
Association of a common polymorphism in the factor XIII gene with venous thrombosis.
Blood - 1 Feb 1999
Catto A J, Kohler H P, Coore J, Mansfield M W, Stickland M H, Grant P J
Abstract excerpt
We have shown an association between a common mutation in the factor XIII a-subunit gene, coding for an amino acid change, 3 amino acids from the thrombin activation site (factor XIII Val34Leu) that may protect against myocardial infarction and predisposes to intracranial hemorrhage. To investigate the possible role of factor XIII Val34Leu in the pathogenesis of venous thromboembolism (VTE) and potential...
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