Article
Direct structural evidence for formation of a stem-loop structure involved in ribosomal frameshifting in human immunodeficiency virus type 1.
Biochimica et biophysica acta - 1 Apr 1998
Kang H
Abstract excerpt
Programmed ribosomal frameshifting in viral messenger RNA occurs in response to neighboring sequence elements consisting of: a frameshift site, a spacer, and a downstream enhancer sequence. In human immunodeficiency virus type 1 (HIV-1) mRNA, this sequence element has a potential to form either a...
Topics
- Endoribonucleases
- Enhancer Elements, Genetic
- Frameshifting, Ribosomal
- HIV-1
- Mutation
- Nucleic Acid Conformation
- RNA, Viral
- Ribonuclease T1
- Single-Strand Specific DNA and RNA Endonucleases
- Ultraviolet Rays
