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Article

Analysis of natural variants of the human immunodeficiency virus type 1 gag-pol frameshift stem-loop structure.

Journal of virology - 1 Aug 2002

Telenti Amalio, Martinez Raquel, Munoz Miguel, Bleiber Gabriela, Greub Gilbert, Sanglard Dominique, Peters Solange

Abstract excerpt

Human immunodeficiency virus type 1 uses ribosomal frameshifting for translation of the Gag-Pol polyprotein. Frameshift activities are thought to be tightly regulated. Analysis of gag p1 sequences from 270 plasma virions identified in 64% of the samples the occurrence of polymorphism that could lead to changes in thermodynamic stability of the stem-loop. Expression in Saccharomyces cerevisiae of...

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Source

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Identifiers

PMID: 12097600
DOI: 10.1128/jvi.76.15.7868-7873.2002
PMCID: PMC136395

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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