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Article

Augmented retinal endothelin-1, endothelin-3, endothelinA and endothelinB gene expression in chronic diabetes

1 Jan 1998

Abstract excerpt

PURPOSE: Endothelins (ETs) belong to a family of vasoactive peptides implicated in several disorders of the microvasculature. In the present study, we investigated ET-1 and ET-3 peptide mRNAs and ETA, ETB receptor mRNAs in the retina of diabetic BB/W rats and age-matched, non-diabetic control animals, following six months of diabetes. METHODS: Total mRNA was extracted from each retina and was subjected to reverse...

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Share to Nitric Oxide and Endothelin Effects
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Identifiers

PMID: 9543639
DOI: 10.1076/ceyr.17.3.301.5216

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