Article
The β3 adrenoceptor in proliferative retinopathies: “Cinderella” steps out of its family shadow
2 Mar 2023
Abstract excerpt
In the retina, hypoxic condition leads to overgrowing leaky vessels resulting in altered metabolic supply that may cause impaired visual function. Hypoxia-inducible factor-1 (HIF-1) is a central regulator of the retinal response to hypoxia by activating the transcription of numerous target genes, including vascular endothelium growth factor, which acts as a major player in retinal angiogenesis. In the present...
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