Article
A functional variant of the serotonin transporter gene in families with bipolar affective disorder.
Journal of affective disorders - 1 Mar 1998
Ewald H, Flint T, Degn B, Mors O, Kruse T A
Abstract excerpt
BACKGROUND: The serotonin transporter protein (SERT) reuptakes serotonin from synapses and has been implied as the site of therapeutic action of many antidepressant drugs. SERT is one of the most relevant candidate genes for bipolar affective disorder. Recently a functionally important 44 basepair deletion in the regulatory region of the SERT gene was described. Association between this variant and affective...
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