Fibroblast-growth-factor receptor mutations in human skeletal disorders.

doi:10.1016/s0168-9525(00)89088-5

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Article

Fibroblast-growth-factor receptor mutations in human skeletal disorders.

Trends in genetics : TIG - 1 Aug 1995

Muenke M, Schell U

Abstract excerpt

Fibroblast-growth-factor receptors (FGFRs), members of the tyrosine-kinase receptor family, play a crucial role in signal transduction and development. Recently, unique mutations in three human FGFR-encoding genes (FGFR1-3) have been identified as the cause of a variety of skeletal disorders. Com...

Topics

Animals
Bone Diseases
Humans
Mutation
Receptors, Fibroblast Growth Factor

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