Article
A genetic screen for elements of the network that regulates neurogenesis in Drosophila.
Molecular & general genetics : MGG - 1 Feb 1998
Röttgen G, Wagner T, Hinz U
Abstract excerpt
The development of external sensory organs on the notum of Drosophila is promoted by the proneural genes achaete and scute. Their activity defines proneural cell clusters in the wing imaginal disc. Ectopic expression, under control of the GAL4 system, of the proneural gene lethal of scute (l'sc) causes the development of ectopic bristles. Persistent ectopic expression of l'sc is not sufficient to impose a neural...
Topics
- Alleles
- Animals
- Basic Helix-Loop-Helix Transcription Factors
- Chromosome Mapping
- DNA Transposable Elements
- DNA-Binding Proteins
- Drosophila Proteins
- Drosophila melanogaster
- Enhancer Elements, Genetic
- Female
- Gene Expression Regulation, Developmental
