Article
Lethal of scute, a proneural gene, participates in the specification of muscle progenitors during Drosophila embryogenesis.
Genes & development - 1 Oct 1995
Carmena A, Bate M, Jiménez F
Abstract excerpt
The mechanisms that underlie the segregation of muscle founder cells in the Drosophila embryo are undefined. We show that the proneural gene lethal of scute (l'sc) is expressed in clusters of cells in the somatic mesoderm, from which individual muscle progenitors are singled out by progressive re...
Topics
- Animals
- Basic Helix-Loop-Helix Transcription Factors
- Cell Differentiation
- Drosophila
- Drosophila Proteins
- Gene Expression Regulation, Developmental
- Genes, Insect
- Homeodomain Proteins
- Mesoderm
- Microscopy, Confocal
- Muscles
- Mutation
- Phenotype
- Proteins
- Stem Cells
- Transcription Factors