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Article

Homology-dependent gene silencing in Paramecium.

Molecular biology of the cell - 1 Apr 1998

Ruiz F, Vayssié L, Klotz C, Sperling L, Madeddu L

Abstract excerpt

Microinjection at high copy number of plasmids containing only the coding region of a gene into the Paramecium somatic macronucleus led to a marked reduction in the expression of the corresponding endogenous gene(s). The silencing effect, which is stably maintained throughout vegetative growth, has been observed for all Paramecium genes examined so far: a single-copy gene (ND7), as well as members of multigene...

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Identifiers

PMID: 9529389
DOI: 10.1091/mbc.9.4.931
PMCID: PMC25319

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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