Article
Defects in type III secretion correlate with internalization of Pseudomonas aeruginosa by epithelial cells.
Infection and immunity - 1 Apr 1998
Hauser A R, Fleiszig S, Kang P J, Mostov K, Engel J N
Abstract excerpt
Previous characterization of Pseudomonas aeruginosa clinical isolates has demonstrated an inverse correlation between cytotoxicity and internalization by epithelial cells. To further investigate this relationship, we tested PA103, a cytotoxic P. aeruginosa strain, and 33 isogenic noncytotoxic transposon mutants for internalization by Madin-Darby canine kidney cells. The majority of the mutants were not...
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