Article
The 18S rRNA dimethylase Dim1p is required for pre-ribosomal RNA processing in yeast.
Genes & development - 15 Oct 1995
Lafontaine D, Vandenhaute J, Tollervey D
Abstract excerpt
The m6(2)A1779m6(2)A1780 dimethylation at the 3' end of the small subunit rRNA has been conserved in evolution from bacteria to eukaryotes. The yeast 18S rRNA dimethylase gene DIM1 was cloned previously by complementation in Escherichia coli and shown to be essential for viability in yeast. A conditional GAL10::dim1 strain was constructed to allow the depletion of Dim1p from the cell. During depletion,...
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