The 18S rRNA dimethylase Dim1p is required for pre-ribosomal RNA processing in yeast.

doi:10.1101/gad.9.20.2470

Back to search

Article

The 18S rRNA dimethylase Dim1p is required for pre-ribosomal RNA processing in yeast.

Genes & development - 15 Oct 1995

Lafontaine D, Vandenhaute J, Tollervey D

Abstract excerpt

The m6(2)A1779m6(2)A1780 dimethylation at the 3' end of the small subunit rRNA has been conserved in evolution from bacteria to eukaryotes. The yeast 18S rRNA dimethylase gene DIM1 was cloned previously by complementation in Escherichia coli and shown to be essential for viability in yeast. A con...

Topics

Base Sequence
DNA Primers
Methylation
Methyltransferases
Molecular Sequence Data
Mutation
RNA Precursors
RNA Processing, Post-Transcriptional
RNA, Ribosomal
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins
Subcellular Fractions

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.