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Article

Differential misclassification and the assessment of gene-environment interactions in case-control studies.

American journal of epidemiology - 1 Mar 1998

García-Closas M, Thompson W D, Robins J M

Abstract excerpt

In case-control studies of interactions between genetic and environmental exposures, differential misclassification of the environmental exposure with respect to disease status can introduce spurious heterogeneity of the stratum-specific odds ratios. In this paper, the authors identify conditions under which differential misclassification does not introduce bias in the interaction parameter when no multiplicative...

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PMID: 9525528
DOI: 10.1093/oxfordjournals.aje.a009467

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Source receipt: pubmed, retrieved 7 Sept 2026.

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