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Article

Different Pattern of MRP Localization in Ciliated and Basal Cells from Human Bronchial Epithelium

1 Apr 1998

Abstract excerpt

The MRP (multidrug resistance-associated protein) transmembrane transporter, which actively transports a wide variety of lipophilic substrates out of cancer cells, has been suggested to play a major role in cell detoxification via efflux of glutathione conjugates. Because bronchial epithelial cells are constantly exposed to environmental pollutants, MRP might be a particularly important defense mechanism against...

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PMID: 9524197
DOI: 10.1177/002215549804600411

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