Article

RT-PCR analysis of ABC, SLC and SLCO drug transporters in human lung epithelial cell models

2009-05-01

Abstract excerpt

Abstract Objectives Carrier-mediated transport mechanisms play crucial roles in drug absorption and elimination processes, as well as in the transport of endogenous molecules affecting cellular regulation and function. In this study we used RT-PCR analysis to characterise the mRNA transcript expression of a wide range of membrane carrier transporters in several in-vitro lung epithelial cell models. Transporters st...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 92426774-f35d-59d2-9cda-d5ab547a884e
DOI: 10.1211/jpp.61.05.0006

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

RT-PCR analysis of ABC, SLC and SLCO drug transporters in human lung epithelial cell modelsDOI 10.1211/jpp.61.05.0006Read

RT-PCR analysis of ABC, SLC and SLCO drug transporters in human lung epithelial cell modelsSemantic proximity Read

Human airway epithelial cell lines for in vitro drug transport and metabolism studiesSemantic proximity Read

Real-Time Reverse Transcription-PCR Expression Profiling of the Complete Human ATP-Binding Cassette Transporter Superfamily in Various TissuesSemantic proximity Read

Expression and Function of ABC Transporters in Human Alveolar Epithelial CellsSemantic proximity Read

Genetic and/or non-genetic causes for inter-individual and inter-cellular variability in transporter protein expression: implications for understanding drug efficacy and toxicitySemantic proximity Read

The impact of cigarette smoke exposure, and COPD or asthma status on ABC transporter gene expression in human airway epithelial cellsSemantic proximity Read

The impact of cigarette smoke exposure, COPD, or asthma status on ABC transporter gene expression in human airway epithelial cellsSemantic proximity Read

Expression analysis of human solute carrier (SLC) family transporters in nasal mucosa and RPMI 2650 cellsSemantic proximity Read

Quantitative expression of human drug transporter proteins in lung tissues: Analysis of regional, gender, and interindividual differences by liquid chromatography–tandem mass spectrometrySemantic proximity Read

Targeted omics analyses, and metabolic enzyme activity assays demonstrate maintenance of key mucociliary characteristics in long term cultures of reconstituted human airway epitheliaSemantic proximity Read

Expression of Thirty-six Drug Transporter Genes in Human Intestine, Liver, Kidney, and Organotypic Cell LinesSemantic proximity Read

ATP-binding cassette (ABC) transporters in normal and pathological lungSemantic proximity Read