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Article

RT-PCR analysis of ABC, SLC and SLCO drug transporters in human lung epithelial cell models

27 Apr 2009

Abstract excerpt

OBJECTIVES: Carrier-mediated transport mechanisms play crucial roles in drug absorption and elimination processes, as well as in the transport of endogenous molecules affecting cellular regulation and function. In this study we used RT-PCR analysis to characterise the mRNA transcript expression of a wide range of membrane carrier transporters in several in-vitro lung epithelial cell models. Transporters studied...

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PMID: 19405996
DOI: 10.1211/jpp/61.05.0006

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