Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Fluorescence-Based Transport Assays Revisited in a Human Renal Proximal Tubule Cell Line

12 Feb 2016

Abstract excerpt

Apical transport is key in renal function, and the activity of efflux transporters and receptor-mediated endocytosis is pivotal in this process. The conditionally immortalized proximal tubule epithelial cell line (ciPTEC) endogenously expresses these systems. Here, we used ciPTEC to investigate the activity of three major efflux transporters, viz., breast cancer resistance protein (BCRP), multidrug resistance...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drug Transport and Resistance Mechanisms
Share to Pharmacological Effects and Toxicity Studies
Share to Pregnancy and Medication Impact

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26871298
DOI: 10.1021/acs.molpharmaceut.5b00821

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fluorescence-Based Transport Assays Revisited in a Human Renal Proximal Tubule Cell LinePMID 26871298Read ↗

Assessment of Human Renal Transporter Based Drug-Drug Interactions Using Proximal Tubule Kidney-ChipSemantic proximity Read ↗

Characterization of Polarized Expression of Point- or Deletion-Mutated Human BCRP/ABCG2 in LLC-PK1 CellsSemantic proximity Read ↗

Structure and function of BCRP, a broad specificity transporter of xenobiotics and endobioticsSemantic proximity Read ↗

The MRP4/ABCC4 Gene Encodes a Novel Apical Organic Anion Transporter in Human Kidney Proximal TubulesSemantic proximity Read ↗

Drugdrug interactions involving membrane transporters in the human kidneySemantic proximity Read ↗

Expression of xenobiotic transporters in the human renal proximal tubule cell line RPTEC/TERT1Semantic proximity Read ↗

Apical membrane targeting and trafficking of the human proton-coupled transporter in polarized epithelia.Semantic proximity Read ↗

Subcellular Localization and Activity of Multidrug Resistance ProteinsSemantic proximity Read ↗

Expression and Function of ABC Transporters in Human Alveolar Epithelial CellsSemantic proximity Read ↗

Pharmacological characterization of the murine and human orthologs of multidrug-resistance protein in transfected human embryonic kidney cells.Semantic proximity Read ↗

A pleiotropic defect reducing drug accumulation in cisplatin-resistant cells.Semantic proximity Read ↗

Fluorescence-based methods for studying activity and drug-drug interactions of hepatic solute carrier and ATP binding cassette proteins involved in ADME-ToxSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.