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Article

BDNF and CNTF regulate cholinergic properties of sympathetic neurons through independent mechanisms.

Molecular and cellular neurosciences - 1 Aug 2003

Slonimsky John D, Yang Bo, Hinterneder Jeanine M, Nokes Eva B, Birren Susan J

Abstract excerpt

Cultured neonatal sympathetic neurons can synthesize and corelease norepinephrine (NE) and acetylcholine (ACh). Evoked release of NE has an excitatory effect on the beat rate of cocultured cardiac myocytes while ACh release results in myocyte inhibition. Here we show that the cholinergic properties of the neurons and the relative level of NE and ACh corelease are modulated by neurotrophic factors. Brain-derived...

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Share to Acetylcholine
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Ciliary Neurotrophic Factor

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Share to Norepinephrine Plasma Membrane Transport Proteins

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Source

Identifiers

PMID: 12932444
DOI: 10.1016/s1044-7431(03)00102-7

Genes

CNTF
BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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