Cell death during development of testis and cerebellum in the mutant mouse weaver.

Abstract excerpt

The murine mutation weaver confers early death during development on cells in testes, cerebellum, and midbrain. The results reported here support the hypothesis that the action of weaver is intrinsic to testes and independent of Sertoli cells: germ cells are the only testicular cell type seen to die in weaver homozygotes, while Sertoli cell-dependent development of the blood testis barrier is normal. This report...

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