Phenotypic effects of the weaver gene are evident in the embryonic cerebellum but not in the ventral midbrain.

doi:10.1016/0165-3806(96)00107-1

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Article

Phenotypic effects of the weaver gene are evident in the embryonic cerebellum but not in the ventral midbrain.

Brain research. Developmental brain research - 23 Oct 1996

Bayer S A, Wills K V, Wei J, Feng Y, Dlouhy S R, Hodes M E, Verina T, Ghetti B

Abstract excerpt

Degeneration of neurons in two structures, the cerebellum and the dopaminergic neurons in the ventral midbrain, is a well characterized action of the weaver gene. In order to see whether the gene has effects prenatally, both the cerebellum and the ventral midbrain were examined in mouse embryos g...

Topics

Animals
Cerebellum
Dopamine
Gene Expression Regulation, Developmental
Genotype
Mesencephalon
Mice
Mice, Neurologic Mutants
Neurons
Phenotype
Purkinje Cells

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