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Article

Clinical Features in Affected Individuals From 21 Pedigrees With Dominant Optic Atrophy

1 Mar 1998

Abstract excerpt

OBJECTIVE: To assess phenotypic variation of affected individuals from British families with autosomal dominant optic atrophy. DESIGN: Eighty-seven patients from 21 families showing evidence of linkage to chromosome 3q were identified via the Genetic Clinic of Moorfields Eye Hospital, London, England. Genetic linkage analysis was carried out with markers from chromosome 3q28-qter. Patients underwent clinical...

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Identifiers

PMID: 9514489
DOI: 10.1001/archopht.116.3.351

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