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Article

Dominant optic atrophy. Refining the clinical diagnostic criteria in light of genetic linkage studies.

Ophthalmology - 1 Jan 1999

Johnston R L, Seller M J, Behnam J T, Burdon M A, Spalton D J

Abstract excerpt

OBJECTIVE: To describe the clinical findings and refine the clinical diagnostic criteria for dominant optic atrophy based on eight British families in which the diagnosis was confirmed by linkage analysis. DESIGN AND PARTICIPANTS: Case series; 92 subjects in 8 pedigrees had both eyes examined. INTERVENTION: Family members received a domiciliary examination based on best-corrected visual acuity, color vision using...

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Identifiers

PMID: 9917792
DOI: 10.1016/S0161-6420(99)90013-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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