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Article

Retinal dysfunction characterizes subtypes of dominant optic atrophy.

Acta ophthalmologica - 1 Mar 2018

Cascavilla Maria Lucia, Parisi Vincenzo, Triolo Giacinto, Ziccardi Lucia, Borrelli Enrico, Di Renzo Antonio, Balducci Nicole, Lamperti Costanza, Bianchi Marzoli Stefania, Darvizeh Fatima, Sadun Alfredo A, Carelli Valerio, Bandello Francesco, Barboni Piero

Abstract excerpt

PURPOSE: To assess preganglionic retinal function using multifocal electroretinogram (mfERG) in patients affected by dominant optic atrophy (DOA) stratified by OPA1 gene mutation. METHODS: Multifocal electroretinogram (mfERG) was recorded in 18 DOA patients (DOA group, 35 eyes) and 25 age-matched healthy subjects (control group, 25 eyes). Patients were stratified in two groups based on gene mutation: missense...

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Source

Identifiers

PMID: 28926202
DOI: 10.1111/aos.13557

Genes

OPA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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