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Article

Dominant optic atrophy

1 Jan 2012

Abstract excerpt

UNLABELLED: DEFINITION OF THE DISEASE: Dominant Optic Atrophy (DOA) is a neuro-ophthalmic condition characterized by a bilateral degeneration of the optic nerves, causing insidious visual loss, typically starting during the first decade of life. The disease affects primary the retinal ganglion cells (RGC) and their axons forming the optic nerve, which transfer the visual information from the photoreceptors to the...

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PMID: 22776096
DOI: 10.1186/1750-1172-7-46

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