Article
Multiple factors interacting at the GATA sites of the gonadotropin-releasing hormone neuron-specific enhancer regulate gene expression.
Molecular endocrinology (Baltimore, Md.) - 1 Mar 1998
Lawson M A, Buhain A R, Jovenal J C, Mellon P L
Abstract excerpt
Neuron-specific expression of the GnRH gene is dependent on an upstream multicomponent enhancer. This enhancer is functional in a small population of GnRH-producing hypothalamic neurons which, through the secretion of GnRH, mediates central nervous system control of reproductive function. GnRH enhancer function requires activation by the GATA family of transcription factors that act through tandem consensus...
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