Article
Molecular features of penicillin allergy.
The Journal of investigative dermatology - 1 Mar 1998
Weltzien H U, Padovan E
Abstract excerpt
Haptens, such as drugs and other low molecular weight chemicals, become immunogenic only upon binding to proteins. Among antibiotics, penicillins are most commonly used for the treatment of bacterial infections and constitute a typical example of allergy inducing drugs in humans. Previous work on their immunologic properties focused mainly on the examination of IgE-mediated hypersensitivity reactions; however,...
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