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Article

Delayed drug hypersensitivity: models of T-cell stimulation.

British journal of clinical pharmacology - 1 May 2011

Adam Jacqueline, Pichler Werner J, Yerly Daniel

Abstract excerpt

Drug-induced hypersensitivity reactions can cause a variety of serious diseases by involving drug-specific T-cells. Many of these reactions have been explained by the hapten concept, which postulates that small chemical compounds need to bind covalently to proteins to be recognized by the immune system. Due to their chemical reactivity, haptens stimulate the innate immunity by binding covalently to endogenous...

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Identifiers

PMID: 21480949
DOI: 10.1111/j.1365-2125.2010.03764.x
PMCID: PMC3093075

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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