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Article

A Retrospective Critical Analysis and Risk Stratification of Penicillin Allergy Delabeling in a UK Specialist Regional Allergy Service.

The journal of allergy and clinical immunology. In practice - 1 Jan 2019

Mohamed Omar E, Beck Sarah, Huissoon Aarnoud, Melchior Cathryn, Heslegrave Jane, Baretto Richard, Ekbote Anjali, Krishna Mamidipudi Thirumala

Abstract excerpt

BACKGROUND: A spurious label of penicillin allergy (Pen-A) negatively impacts on antibiotic stewardship and health care costs. Recent studies have proposed a guideline-steered direct penicillin challenge without undertaking allergy tests when "true allergy" is unlikely. OBJECTIVE: To critically analyze Pen-A clinical presentation, perform risk stratification, and determine clinical predictors for "true allergy."...

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Identifiers

PMID: 29883754
DOI: 10.1016/j.jaip.2018.05.025

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