Article
Dominant alleles of Saccharomyces cerevisiae CDC20 reveal its role in promoting anaphase.
Genetics - 1 Feb 1998
Schott E J, Hoyt M A
Abstract excerpt
We identified an allele of Saccharomyces cerevisiae CDC20 that exhibits a spindle-assembly checkpoint defect. Previous studies indicated that loss of CDC20 function caused cell cycle arrest prior to the onset of anaphase. In contrast, CDC20-50 caused inappropriate cell cycle progression through M...
Topics
- Alleles
- Amino Acid Sequence
- Anaphase
- Cdc20 Proteins
- Cell Cycle Proteins
- Flow Cytometry
- Fungal Proteins
- Gene Expression Regulation, Fungal
- Genes, Dominant
- Molecular Sequence Data
- Mutation
- Nuclear Proteins
- Phenotype
- Protein Serine-Threonine Kinases
- Protein-Tyrosine Kinases
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Securin