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Article

Dominant alleles of Saccharomyces cerevisiae CDC20 reveal its role in promoting anaphase.

Genetics - 1 Feb 1998

Schott E J, Hoyt M A

Abstract excerpt

We identified an allele of Saccharomyces cerevisiae CDC20 that exhibits a spindle-assembly checkpoint defect. Previous studies indicated that loss of CDC20 function caused cell cycle arrest prior to the onset of anaphase. In contrast, CDC20-50 caused inappropriate cell cycle progression through M phase in the absence of mitotic spindle function. This effect of CDC20-50 was dominant over wild type and was...

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Identifiers

PMID: 9504909
DOI: 10.1093/genetics/148.2.599
PMCID: PMC1459839

Genes

CDC20
APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Dominant alleles of Saccharomyces cerevisiae CDC20 reveal its role in promoting anaphase.PMID 9504909Read ↗

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