Applicability of nonsyngeneic cell models for screening of genes in monogenetic diseases via differential display technique.

doi:10.1002/elps.1150181525

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Article

Applicability of nonsyngeneic cell models for screening of genes in monogenetic diseases via differential display technique.

Electrophoresis - 1 Dec 1997

Planitzer S A, Machl A W, Kubbies M

Abstract excerpt

Conventional subtraction library techniques or DNA-transfection studies are standard techniques applied for identification and isolation of genes relevant in monogenetic diseases like Fanconi anemia (FA). The differential display technique (DDT) was developed to compare mRNA expression between a...

Topics

Bromodeoxyuridine
Cell Cycle
Cell Division
Cell Line
Data Display
Diploidy
Fanconi Anemia
Fibroblasts
Genetic Testing
Genotype
Humans
Models, Genetic

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