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Article

Applicability of nonsyngeneic cell models for screening of genes in monogenetic diseases via differential display technique.

Electrophoresis - 1 Dec 1997

Planitzer S A, Machl A W, Kubbies M

Abstract excerpt

Conventional subtraction library techniques or DNA-transfection studies are standard techniques applied for identification and isolation of genes relevant in monogenetic diseases like Fanconi anemia (FA). The differential display technique (DDT) was developed to compare mRNA expression between a mutant cell line and its syngeneic control and allows comparison of almost all mRNA species within a short time....

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PMID: 9504823
DOI: 10.1002/elps.1150181525

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DDT

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