Article
Screening for mutations in the neuropeptide Y Y5 receptor gene in cohorts belonging to different weight extremes.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity - 1 Feb 1998
Rosenkranz K, Hinney A, Ziegler A, von Prittwitz S, Barth N, Roth H, Mayer H, Siegfried W, Lehmkuhl G, Poustka F, Schmidt M, Schäfer H, Remschmidt H, Hebebrand J
Abstract excerpt
OBJECTIVE: The neuropeptide Y (NPY) Y5 receptor is presumed to be involved in the regulation of food intake. DESIGN: To investigate the possible role of this receptor in weight regulation, the whole coding region of the NPY Y5 receptor gene was screened for mutations using temperature gradient gel electrophoresis (TGGE). Detected mutations were screened in extended cohorts. STUDY COHORTS AND METHODS: Cohorts of...
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