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Article

Inferring the recent ancestry of myostatin alleles affecting muscle mass in cattle.

Animal genetics - 1 Feb 2013

O'Rourke B A, Greenwood P L, Arthur P F, Goddard M E

Abstract excerpt

Double muscling is an inherited condition in cattle characterised by large increases in muscle mass. Mutations in the myostatin (MSTN) gene, responsible for double muscling, were targeted in this study to estimate the time since the most recent common ancestor (TMRCA) for Q204X (p.Gln204*), E226X (p.Glu226*), 821del11 (c.821del11), E291X (p.Glu291*), C313Y (p.Cys313Tyr) and the more phenotypically moderate F94L...

Topics

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Alleles
Breeding
Cattle
Evolution, Molecular
Haplotypes
Muscle Development

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymerase Chain Reaction

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Identifiers

PMID: 22497537
DOI: 10.1111/j.1365-2052.2012.02354.x

Genes

MSTN

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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