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Article

Xrel3/XrelA attenuates β-catenin-mediated transcription during mesoderm formation in Xenopus embryos.

The Biochemical journal - 1 Apr 2011

Kennedy Mark W L, Kao Kenneth R

Abstract excerpt

In Xenopus laevis embryonic development, activation of the Wnt/β-catenin pathway promotes mesoderm cell fate determination via Xnr (Xenopus nodal-related) expression. We have demonstrated previously that Rel/NF-κB (nuclear factor κB) proteins expressed in presumptive ectoderm limit the activity of Xnrs to the marginal zone of embryos during mesoderm induction, which assists to distinguish mesoderm from ectoderm....

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Identifiers

PMID: 21214516
DOI: 10.1042/BJ20101801

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Xrel3/XrelA attenuates β-catenin-mediated transcription during mesoderm formation in Xenopus embryos.PMID 21214516Read ↗

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