Article
Reciprocal expression of myelin-associated glycoprotein splice variants in the adult human peripheral and central nervous systems.
Brain research. Molecular brain research - 15 Dec 1997
Miescher G C, Lützelschwab R, Erne B, Ferracin F, Huber S, Steck A J
Abstract excerpt
The L- and S-MAG isoforms differ only at their C-terminus and are believed to be functionally distinct. To obtain information on the relative expression of these alternatively spliced isoforms in humans, we cloned an S-MAG cDNA fragment. The deduced amino-acid sequence of the human S-MAG C-terminus shows fairly conservative substitutions of 4 out of the 10 residues compared to the rodent peptide. Using reverse...
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