Article
Lack of evidence for an association between alpha-adducin and blood pressure regulation in Asian populations.
American journal of hypertension - 1 Jun 2000
Ranade K, Hsuing A C, Wu K D, Chang M S, Chen Y T, Hebert J, Chen Y I, Olshen R, Curb D, Dzau V, Botstein D, Cox D, Risch N
Abstract excerpt
Recent studies have found the tryptophan allele of a glycine to tryptophan polymorphism at position 460 (G460W) of the alpha-adducin protein to be associated with essential hypertension in European populations. We examined whether the tryptophan allele is associated with hypertension in a different population, comprised of subjects of Chinese origin from Taiwan, and Chinese and Japanese origin from the San...
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