Article
The development of antibody responses in the infant.
Immunology and cell biology - 1 Dec 1997
Zola H
Abstract excerpt
The human infant is a major subject of immunization to prevent infectious disease. A better understanding of immune responses in human infants could lead to more effective immunization. Analysis of individual mechanisms is a prerequisite to understanding the whole response. We have examined the mutation and selection of immunoglobulin genes, mechanisms required for the maturation of antibody affinity. Mutations...
Topics
- Adult
- Humans
- Immunoglobulins
- Infant
- Mutation
- Receptors, Antigen
- Receptors, Cytokine
- Selection, Genetic
