Article
The lectin-like NK cell receptor Ly-49A recognizes a carbohydrate-independent epitope on its MHC class I ligand.
Immunity - 1 Feb 1998
Matsumoto N, Ribaudo R K, Abastado J P, Margulies D H, Yokoyama W M
Abstract excerpt
The mouse NK inhibitory Ly-49A receptor specifically interacts with a peptide-induced conformational determinant on its MHC class I ligand, H-2Dd. In addition, it binds the polysaccharide fucoidan, consistent with its C-type lectin homology and the hypothesis that Ly-49A interacts with carbohydra...
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