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Article

Ligand interactions by activating and inhibitory Ly-49 receptors.

Immunological reviews - 1 Jun 2001

Nakamura M C, Seaman W E

Abstract excerpt

Natural killer (NK) cells express families of homologous receptors, members of which either activate or inhibit NK cells. We demonstrate that mouse Ly-49D is an activating receptor for the MHC antigen H2-Dd, which is also a ligand for the related inhibitory receptor Ly-49A. To compare and contrast their interactions with class I MHC ligand, we studied each of these receptors expressed in a rat NK-cell hne,...

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Share to Antigens, Ly
Share to H-2 Antigens
Share to Histocompatibility Antigen H-2D

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Histocompatibility Antigens Class I

Share to Killer Cells, Natural

Share to Lectins, C-Type

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Source

Identifiers

PMID: 11513135
DOI: 10.1034/j.1600-065x.2001.1810111.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Ligand interactions by activating and inhibitory Ly-49 receptors.PMID 11513135Read ↗

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Allelic variation in the ectodomain of the inhibitory Ly-49G2 receptor alters its specificity for allogeneic and xenogeneic ligands.Semantic proximity Read ↗

Ly49A allelic variation and MHC class I specificity.Semantic proximity Read ↗

Reciprocal transfer of class I MHC allele specificity between activating Ly-49P and Ly-49W receptors by exchange of beta 4-beta 5 loop residues.Semantic proximity Read ↗

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Crystal structure of the Ly49I natural killer cell receptor reveals variability in dimerization mode within the Ly49 family.Semantic proximity Read ↗

Ly-49 receptors and their functions.Semantic proximity Read ↗

Direct assessment of MHC class I binding by seven Ly49 inhibitory NK cell receptors.Semantic proximity Read ↗

The Ly-49D Receptor Activates Murine Natural Killer CellsSemantic proximity Read ↗

H-2 allele specificity of the NK cell C-type lectin-like MHC class I receptor Ly49A visualized by soluble Ly49A tetramer.Semantic proximity Read ↗

The NK2.1 receptor is encoded by Ly-49C and its expression is regulated by MHC class I alleles.Semantic proximity Read ↗

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