Article
Ectopic and increased expression of Fasciclin II alters motoneuron growth cone guidance.
Neuron - 1 Sept 1994
Lin D M, Goodman C S
Abstract excerpt
We used the enhancer detection/GAL4 system in Drosophila to direct increased levels of Fasciclin II (Fas II) expression on motoneuron growth cones and axons and to direct ectopic Fas II expression on other cells they encounter. Four classes of abnormal phenotypes are observed: "bypass" phenotypes, in which axons fail to defasciculate at the choice point where they would normally enter their muscle target region...
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