Article
Predisposition of Wolfram syndrome heterozygotes to psychiatric illness.
Molecular psychiatry - 1 Jan 1998
Swift R G, Polymeropoulos M H, Torres R, Swift M
Abstract excerpt
Identification of specific genes that predispose to psychiatric illness will lead to more precise psychiatric diagnosis and more effective treatment. Heterozygous carriers of genes for many autosomal recessive syndromes may be 1% or more of the general population. Thus, if mutations at a specific locus produce psychiatric manifestations in homozygous affected individuals, it is important to determine whether...
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