Article
Is there a relationship between Wolfram syndrome carrier status and suicide?
American journal of medical genetics - 8 Apr 2002
Crawford Joanna, Zielinski Marta A, Fisher Laura J, Sutherland Grant R, Goldney Robert D
Abstract excerpt
Wolfram syndrome (WFS) is a rare, autosomal recessive neurodegenerative disorder. An increased risk of psychiatric disorders and suicide has been reported for heterozygote carriers. In this study we investigated whether mutations in the WFS gene are associated with suicide in the general population. The gene for WFS (WFS1) has recently been mapped to chromosome 4p16.1, and its genomic structure has been...
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